Drug-induced loss of imprinting revealed using bioluminescent reporters of Cdkn1c
Abstract Genomic imprinting is an epigenetically mediated mechanism that regulates allelic expression Fridge Gas Drier of genes based upon parent-of-origin and provides a paradigm for studying epigenetic silencing and release.Here, bioluminescent reporters for the maternally-expressed imprinted gene Cdkn1c are used to examine the capacity of chroma